Difference between Juvederm and Restylane

Juvederm and Restylane are hyaluronic acid-based dermal fillers used for treating wrinkles and augmenting lips. The surface results of both the products appear to be the same. These injectable dermal fillers provide volume replacement benefits, reducing wrinkles and lifting the skin. Both treatments are non-surgical, pain-free, and have no downtime.

While Juvederm and Restylane come with the same essential ingredients, they differ in texture, usage, costs, and other factors.

What is Restylane?

Restylane is an FDA-approved dermal filler made from biodegradable hyaluronic acid. The hyaluronic acid in Restylane is produced biotechnologically through natural fermentation of streptococcus species of bacteria in a sterile laboratory setting. Therefore, it is considered safer than standard hyaluronic acids, generally produced by animal sources.

This significantly eliminates the chances of transmitting disease from other species and is safe for patients having allergic reactions to common foods such as beef, eggs, and chicken. 

Restylane is available in a clear gel offering a dual mechanism of action to treat moderate to severe wrinkles and folds. The gel safely integrates with dermal tissues and binds to water molecules when injected under the skin, providing natural volume. Plus, it naturally degrades and disappears from the body without residue. 

What is Juvederm?

Juvederm is an injectable hyaluronic acid dermal filler to correct moderate to severe facial wrinkles and folds such as nasolabial folds located around the nose to the corners of the mouth. Some range of Juvederm is also used for lip augmentation.

Juvederm is produced via Hylacross Technology from bacterial fermentation called Non-Animal Stabilized Hyaluronic Acid (NASHA), similar to Restylane. It is available in smooth consistency gel in various ranges and formulations for specific treatment purposes. 

For instance, the Juvederm XC range comes with local anesthetic lidocaine to numb the treatment area within seconds. The Juvederm Ultra XC products, on the other hand, come integrated with highly cross-linked formulations to treat and volumize deeper folds and wrinkles.

Difference between Juvederm and Restylane

FactorsJuvedermRestylane
Range of ProductsJuvderm ranges of products include: Juvederm Voluma® XC: Deep injection for treating age-related volume loss and chin augmentation. Juvederm Vollure™ XC/ Juvederm ® Ultra Plus XC: Facial injection for correction moderate to severe facial wrinkles and folds.  Juvederm® Ultra XC: Facial injection for treating moderate to severe facial wrinkles, folds and for lips augmentation. Juvederm® XC: Injection for correcting moderate to severe facial folds, wrinkles such as parentheses lines (folds running from nose to mouth). Juvederm Volbella® XC: Injection for lip augmentation, correction of perioral lines, improving under eye hollows.Restylane ranges of products include: Restylane Defyne: Injection for deep lines and laugh lines. Restylane Refyne: Treatment for moderate smiles and laugh lines. Restylane®: Facial injection for facial wrinkles and folds. Restylane Silk: Treatment lips and lines around them. Restylane Lyft: Injection for facial wrinkles, cheeks and back of the hands.
ResultsThe results of Juvederm is instant.You will get the results within a few days (usually 24-48 hours) after the procedure.
Results DurationJuvederm tends to last longer around a year to a year and half.Restylane lasts for around 9-10 months.
CostsJuvederm costs slighter higher than Restylane. Plus, it depends upon the provider and the region of treatment as well. For instance, a provider on the East Coast charges Volbella XC at $550 per syringe, while the price ranges in between $600-$900 per injection at California.Restylane costs lower than Juvederm and the region of the treatment also affects the price. Restylane Silk costs between $300-$600 per injection depends on the area of treatment. In the West Coast, you may pay $650 per 1ml injection while at New York you have to pay $550 per syringe.
TextureJuvederm has a smoother texture, making it ideal for finer lines and wrinkles for tight facial areas.Restylane has a granular texture and more cohesive that Juvederm, allowing it to stay in place. It helps in adding volumes in sunken facial areas. It is also more moldable, enabling professionals to create better shapes and contour.
Treatment AreasIt comes with different formulas targeting different facial areas including the eyes, cheeks, and mouth. More potent ranges like the Vollure is specially formulated to target severe wrinkles and folds including the nasolabial folds.It addressed several facial areas as Juvederm, but mostly effective in treating lips, cheeks and nose areas.

Which is better? Juvederm or Restylane?

Juvederm and Restylane come with specially formulated biodegradable hyaluronic acid, which is considered the safest form of non-invasive treatment for wrinkles, folds, and lips augmentation. So if you have to select the better of the two, you must decide based on your requirements. For severe folds and wrinkles, Juvederm will do a fantastic job. Meanwhile, for lips, Restylane Silk is usually preferred by professionals. Restylane may cost you less, but the results last longer in Juvederm.

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